The Mendelian Randomization by Millwood et al.: Observations and Expressions of Concern

May 6, 2019

Link to article 2, explaining Mendelian Randomization The recent population study of adults in China that found no cardio-protective benefits of moderate alcohol consumption should be re-examined in the context of methodological and confounding factors not addressed in the published paper. Published in early April by The Lancet, the study provoked sensational headlines among the […]

Background: Mendelian Randomization (MR): A new statistical regime to estimate causation

Link to main article Mendelian Randomization (MR) is a relatively new statistical method designed to provide an estimate of a causal connection between the effects of an observable exposure to a risk factor (such as alcohol consumption) on a specific outcome (such as cardiovascular events like stroke and heart attacks). It is necessary to note […]